Warframe

Let's make note of some things.

Combined Damage Types

Blast = Heat + Cold = Some AOE
Corrosive = Elec + Toxin = Armor shredding
Gas = Heat + Toxin = Gas cloud DOTs
Magnetic = Cold + Elec = Shield shredding
Radiation = Heat + Elec = Confusion effect
Viral = Cold + Toxin = Boosts HP damage

Relic Cracking Goals

Wisp Prime (Vaulted): Have Neuroptics & Systems, need Chassis and oh yeah the blueprint.
Dethcube Prime (Vaulted): Have Carapace, need everything else (bloop, Cerebrum, Systems).
Akjagara Prime (Vaulted): Welp.
Euphona Prime (Vaulted): Have Blueprint and Barrel, need Receiver but...

Frames

Tenno Lab Basics

Volt is 30. Nezha is cooking in the foundry. Still need Banshee, Wukong, and Zephyr.

Main Roster

Caliban is a hybrid, has a baby version of Rhino Stomp but also has pet summons, in addition to giant laser beam.
Xaku is the anti-Sentient guy but really, an all-around delight. Void damage boost to all attacks for a bit, a "steal yer guns" power, and a "Terminator mode".
- Stole Nyx's mind-control power via the Helminth into the A and B loadouts. First trial run? During The Hex.
Rhino P is obviously a keeper. Made to be tanky, delights in being stompy. But more importantly, 3 equals damage.
Mesa is the gunslinger, and we Helminth'd Xata's Whisper for some weapon damage boost. Plus 50% movement speed during the "nuke" is a godsend.
Titania P can turn into a tiny Archwing complete with high-damage weapon. Awesome. Great for certain MR tests, too.
Ivara P (w/ Dread bow) is our stealth (Spy mission) champion.
Vauban is the Excavation & possibly Defense master with his little zot rollers and the Suck Grenade.

Others

Garuda's... weird? Melee-ish?
Octavia is the rhythm nation. Nice one-two combo with the enemy-seeking rollerball (2) and the AOE damage (1) that stick together if cast close enough. Great enemy distraction technique.

Weapons

Primaries

Cedo Prime (Shotgun) - Alt-fire sends a glaive out ahead to status-effect everything you see, which primes the main fire to do ridonkulous damage. In contention for best shotty with...
Kuva Sobek (Shotgun) - Room-cleaner extraordinaire. Can be accurate at range, lots of tasty AOE at whatever distance you like.
Amprex (Rifle) - Zot gun, chain lightning. The "StatStick" mod loadout is ridiculously fun.
Tenet Arca Plasmor (Shotgun) - Super duper shotgun, we got Impact as the "bonus" damage type.
- MagNeato build:

Galvanized Hell	Primed Tactical Pump	Shell Shock	Frigid Blast	Primary Merciless
Atomic Fallout	Vicious Spread	Galvanized Savvy	Magnetic Strafe	Galvanized Acceleration

Kuva Drakgoon (Shotgun) - It's the UT Flak Cannon. It just is. We even have the skin to prove it.
- Main config:

Galvanized Hell	Primed Point Blank	Frigid Blast	Primed Tactical Pump	Primary Merciless
Galvanized Savvy	Magnetic Strafe	Atomic Fallout	Scattering Inferno	Galvanized Acceleration

Dread (Bow) - Hard to pick the favorite bow but we do have Incarnon on the Dread.

Secondaries

Kuva Nukor - The one-handed Amprex we never knew we needed.
Aksomati Prime (sidearm) is a pair of Uzis, basically. Great paired with Amprex which is shorter-ranged.
- BlastCrit build:

Primed Heated Charge	Frostbite	Galvanized Diffusion	Suppress	Secondary Merciless
Lethal Torrent	Hornet Strike	Primed Pistol Gambit	Primed Target Cracker	Steady Hands

Melee

Stropha - (Shot)gunblade. Absolute go-to pick. Ridiculously fun.
Broken Scepter - The plot stick is a nice spin-to-win, if not godly.

Mats

Cryotic means Excavations. Tikal on Earth seems fine, Vauban's self-propelled rolling traps are a BIG help.

Argon Crystal means running missions in the Void. Luckily they drop like candy, so when we need a few, just go do a few Exterminate runs.

Ayatan Treasures

Fill them while in inventory (for some reason Ayatan Treasures is in the Mods menu), then place in Orbiter or sell for Endo.